I've had the tires on for about a month now and I am happy with them. For some context, tires I've had on the truck include Toyo Open Country AT load class E, BF Goodrich Rugged Trail TA (stock), and Blizzak winters. The most recent summers that were on the truck were the BFGs. The new Goodyear's are hands down the best riding tire I've had on the truck, including the Blizzaks. The TRD Tundra is fairly harsh riding and the new tires have softened the ride up. I haven't noticed a decrease in handling but I don't exactly push the truck in the corners. Wet traction is improved off the line. The BFG's were terrible with this. Always seemed to be spinning leaving a light if the road was wet. I haven't had the truck off the beaten path yet, just pavement and a small amount of gravel so I can't comment yet on that aspect.
On the down side, tire noise at highway speed has increased. Not a "hum" like from mud tires, but a noticeable increase, however not bothersome.
One thing I forgot to mention is that I ended up going with a load class "C" tire. This was based on both shops (the one I walked out on and the one I purchased from) recommending a C over an E. Their argument was that an E was overkill for my half ton, which they are probably correct. Part of the argument was that a C is somewhere above the 114 load index rating that are stock on my Tundra and and E load class. I found out afterwards that this isn't the case, a bit of an explanation in the paragraph below. At first I was a little miffed, but after feeling how much the ride improved with the tires I decided I would stick with them. Load carrying capacity of the tires is well over the axle rating anyhow.
Load class "C" gives a load carrying capacity very close to the 114 load index (actually slightly less). However, the load class C is a designated LT tire, which gives heavier duty sidewall construction and extra tread depth. Why the sturdier sidewall construction doesn't equate to a heavier load rating I don't have an answer to. The "load class" and "load index" is confusing. Basically load class is used for LT tires and load index for passenger tires, as I understand it. I don't understand why everything just doesn't follow load index nowadays.
Anyway, happy so far. I'll also have to see how they perform towing our RV trailer which is about 6800lbs dry, so it'll be pushing 8000lbs loaded.