The last generation was strange, we have one and have also had the misfortune to have some as rental cars as well.
We love ours - it rides well (though a little firm for me), it has great acceleration, it's quiet, refined, has good seats and an excellent sound system. We've been doing quite a bit of highway driving recently, so our economy is averaging between 7 and 7.5 (also warmer temperatures have helped). The interior is holding up very well, we're at almost 80k, nothing broken, nothing scratched, nothing squeaking. We have a 2009 SE-R with the CVT. Great car and my in-laws like it if we have to borrow their odyssey for any reason, because they like how it drives, it picks up speed well etc etc.
All of the rental cars we've had are the 2.0 poverty spec that inevitably smell funny. The 2.0 doesn't seem to suit the CVT like the 2.5 does, the uprated shocks on the SE-R seem to control the ride from float better, the seat fabric is better in higher specs etc etc.
It seems as though the last generation is very trim sensitive.
Interestingly, what pushed me originally towards testing the SE-R was discs front and rear (the 2.0 were drum at the back) - testing the two back to back we noticed not only improved braking, but also improvements elsewhere that were well worth the upgrade. For about $1k we couldn't go wrong. On fuelly our car is competitive with 2.0s for fuel economy.
Shame there will be no SE-R on the new one, at least they've so far said there won't be. The 1.6 turbo from the Juke would be fun.