Harrisburg, PA is one of my favorite spots on trips to and from Florida. I like the Days Inn on North Front Street, just off exit 66 on I81. A bit more expensive ($65. with coupon) but the included hot breakfast is one of the best and the place is quiet.
We also always pick up the Hotel Coupons from Rest Areas of states we plan to stay for the night. Very useful but not always honored on week-ends or holidays or when there are said special events in the area.
Never took the time to visit the city and area though.
LOL, Scranton. Stayed once at a Days Inn there and the sole comment I put on the bill was: Didn't like the place...