MD, I doubt the Honda ECU learning your driving habits are going to solve this light hesitation. Typically the learning strategy has more to go with the trans shifting strategy on a short term based on how you are driving at that moment.
What you describe can be related to the lean strategy when cruising or the torque converter clutch modulation. And in your case, add the cylinder deactivation on top of that. I would definitely suggest to monitor TSBs... A future reflash might be in order.